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翻訳と辞書　辞書検索 [ 開発暫定版 ] スポンサード リンク Anti-centromere antibodies ： ウィキペディア英語版 Anti-centromere antibodies Anti-centromere antibodies (ACA) occur in auto immune disorders; frequently in limited systemic scleroderma, (formerly called CREST syndrome), and, occasionally are found in the diffuse form of scleroderma. They are rare in other rheumatic conditions and in healthy persons. Anti-centromere antibodies are found in approximately 60% of patients with limited systemic scleroderma, and in 15% of those with diffuse form of scleroderma. The specificity of this test is >98%. Thus, a positive anticentromere antibody finding is strongly suggestive of limited systemic scleroderma. Anti-centromere antibodies present early in the course of disease, and is notably predictive of limited cutaneous involvement and a decreased likelihood of aggressive internal organ involvement, such as lung fibrosis.〔JB Imboden, DB Hellmann, JH Stone. ''Current Rheumatology Diagnosis & Treatment'', Second Edition. McGraw-Hill, 2007.〕 When present in primary biliary cirrhosis, ACA are prognostic of portal hypertension such that serum ACA levels correlate with the severity of portal hypertension. ==References== 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Anti-centromere antibodies」の詳細全文を読む スポンサード リンク 翻訳と辞書 : 翻訳のためのインターネットリソース Copyright(C) kotoba.ne.jp 1997-2016. All Rights Reserved.